Blar i forfatter "Berland, Léa"

Viser treff 1-2 av 2

    • 17β-estradiol promotes extracellular vesicle release and selective miRNA loading in ERα-positive breast cancer 

      Drula, Rares; Pardini, Barbara; Fu, Xiao; De Los Santos, Mireia Cruz; Jurj, Ancuta; Pang, Lan; El-Daly, Sherien M.; Fabris, Linda; Knutsen, Erik; Dragomir, Mihnea P.; Bayraktar, Recep; Li, Yongfeng; Chen, Meng; Del Vecchio, Filippo; Berland, Léa; Dae, Jessica; Fan, Daniel; Shimizu, Masayoshi; Tran, Anh M.; Barzi, Mercedes; Pioppini, Carlotta; Gutierrez, Angelica M.; Ivan, Cristina; Meas, Salyna; Hall, Carolyn S.; Alahari, Suresh K.; Berindan-Neagoe, Ioana; Fabbri, Muller; Lucci, Anthony; Arun, Banu; Anfossi, Simone; Calin, George A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-30)
      The causes and consequences of abnormal biogenesis of extracellular vesicles (EVs) are not yet well understood in malignancies, including in breast cancers (BCs). Given the hormonal signaling dependence of estrogen receptor–positive (ER+) BC, we hypothesized that 17β-estradiol (estrogen) might influence EV production and microRNA (miRNA) loading. We report that physiological doses of 17β-estradiol ...

    • FuncPEP: A Database of Functional Peptides Encoded by Non-Coding RNAs 

      Dragomir, Mihnea Paul; Manyam, Ganiraju C; Ott, Leonie Florence; Berland, Léa; Knutsen, Erik; Ivan, Cristina; Lipovich, Leonard; Broom, Bradley M.; Calin, George A (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-23)
      Non-coding RNAs (ncRNAs) are essential players in many cellular processes, from normal development to oncogenic transformation. Initially, ncRNAs were defined as transcripts that lacked an open reading frame (ORF). However, multiple lines of evidence suggest that certain ncRNAs encode small peptides of less than 100 amino acids. The sequences encoding these peptides are known as small open reading ...